Hi Daniel.
there is some variation between airlines, but most common use for takeoff would be:
1st bug to 80kts, second bug to V1, third bug Vr, set speed cursor to V2, fourth bug to V2+15 (this is the speed that is minimum for going over 15 deg bank), fifth bug to 170 (for flaps 5 and 15 takeoffs), this is the speed to retract 5 to 1.
For landing we set 1st bug to Vref, speed cursor to target speed, second bug to Vref + 15 (min speed for going over 15 deg bank) and i often set another bug right next to the second one if planning a flaps40 approach (as a reminder).
Cheers, Jan