Ok ... I think I've gotten to the bottom of it, at least in my case. My Saitek switch panel, which I partially use for lights only was setup with the default Spad profile, which includes Avionics On/Off commands for the Av Master switch. I didn't actually verify this by watching the datarefs and events, but I think when I flick the the strobe light on for the very first time Spad tries to sends some commands for all the switches to sync their state ... and since the Av Master switch is physically in the OFF state it must be sending an Avionics Off event.
So, basically flipping the Av Master switch on my panel flips between the low power state and normal state. Working as intended lol >.>
So for me the answer is to simply unbind the Av Master switch. I can't speak to @HamSammich since he/she says they're not running panels. It may be something Toto/Goran want to fix under the covers, but that's obviously up to them.
Thanks for the help with this guys.