I thought I had it narrowed down to a conflict between Xsquawbox and SkyMaxx Pro, but then I realized the only time XP10 crashed to desktop (immediate, no crash log generated, oddly) was when I was flying the MU-2B. I could fly the BK-117 for more than an hour with no crash, but about 15 or 20 minutes after changing to the MU-2B, right after a weather update, it would crash. I began pondering if it could be a Gizmo related issue, as both SkyMaxx and the plane rely on Gizmo. But, I have already sunk enough time and money into this to pursue it further. The final resolution for me was to uninstall SkyMaxx, as all other combinations of my few plugins play nice together, regardless of airplane chosen. In doing so, however, the SkyMaxx uninstall broke the MU-2B. My guess is that the uninstall removed Gizmo completely, despite my having four other X-Aviation packages installed. A re-download and re-install of the MU-2B brought it back to working status. Since removing SkyMaxx, I've booked a significant amount of time--for me--in XP10 without a single crash.